Application of <i>Caenorhabditis elegans</i> in the evaluation of food nutrition: A review

At present, more and people are suffering from various diseases it is particularly important to find a suitable biological model evaluate the prevention treatment effects of drugs active ingredients on diseases. In all models, Caenorhabditis elegans kind organism that easy observe cultivate, has clear genetic background high degree signal pathway conservation with humans. A variety such as polyphenols, polysaccharides, polypeptides, vitamins exist natural products, which extremely physiological functions medicinal values. It highly reliable trophic functional properties products in C. elegans. The antiaging, anti-oxidation, regulating lipid metabolism, preventing treating Alzheimer's disease were clarified this review. same time, its possible pathways summarized. literature revealed had great effect nutrition functionality Finally, shortcomings field suggestions for further improvement have been emphasized.